Controlled release succinic acid microcapsules coated with aqueous acrylics
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United States of America Patent
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Mar 7, 1995
Issued Date -
N/A
app pub date -
Apr 13, 1992
filing date -
Dec 28, 1989
priority date (Note) -
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Abstract
A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and water-slightly permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.
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