Process for producing simvastatin and analogs thereof

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United States of America Patent

PATENT NO 5393893
SERIAL NO

08148517

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A process is disclosed for the preparation of simvastatin and its analogs through a novel intermediate (III), which enables a selective .alpha. carbon alkylation of the C-8 acyl side chain.

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Patent Owner(s)

Patent OwnerAddress
APOTEX INCTORONTO ONTARIO M9L 1T9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kubela, Rudolf Stouffville, CA 7 40
Radhakrishnan, Jayaramaiyer Winnipeg, CA 3 22

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