4,16-diazatetracyclo[23.3.1.1.Hu 14,17=b . 0 Hu 4,9 triaconta-16,19-diene-2,3,10-trione derivatives
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United States of America Patent
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Jan 24, 1995
Grant Date -
N/A
app pub date -
Feb 18, 1993
filing date -
Aug 18, 1990
priority date (Note) -
Expired
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Importance
Abstract
Compounds of formula (I) are provided, wherein R.sup.1 represents OH or OCH.sub.3 ; R.sup.2 represents OH or H; R.sup.3 represents methyl, ethyl, propyl or allyl; X represents O, (H,OH) or (H,H); m represents 0 or 1; n represents 1 or 2; and pharmaceutically acceptable derivatives thereof; provided that when n is 1, then R.sup.3 is allyl or propyl. The compounds are indicated inter alia as immunosuppresive agents. ##STR1##
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