Process for the preparation of ergoline derivatives

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United States of America Patent

PATENT NO 5382669
SERIAL NO

08028286

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Abstract

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The invention provides a process for the preparation of ergoline derivatives of the formula I ##STR1## the process comprising reacting an ergoline amide of the formula II with an isocyanate of formula III ##STR2## in presence of a metal catalyst and of a phosphorus compound. The compounds of the formula I are useful antiprolactinic and antiparkinson agents.

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Patent Owner(s)

Patent OwnerAddress
PHARMACIA & UPJOHN S P AVIA ROBERT KOCH 1/2 MILAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bedeschi, Angelo Milan, IT 41 168
Cabri, Walter Rozzano, IT 98 224
Candiani, Ilaria Busto Arsizio, IT 30 107
Zarini, Franco Settimo Milanese, IT 21 87

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