Enhanced maintenance of pregnancy using leukaemia inhibitory factor in embryo culturing
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United States of America Patent
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Nov 22, 1994
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N/A
app pub date -
Apr 16, 1992
filing date -
Jul 9, 1990
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Expired
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Abstract
The present invention relates to the use of leukemia inhibitory factor (LIF) in the enhancement of development and maintenance of mammalian embryos, particularly sheep embryos. It has been observed that following the introduction into foster mothers of embryos cultured in vitro in the presence of LIF, the maintenance of pregnancy is enhanced relative to that seen following introduction of embryos that had not been cultured with LIF prior to introduction into foster mothers.
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