Recombinant DNA processes for producing PI-linked lymphocyte function associated antigen-3
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United States of America Patent
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Oct 11, 1994
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N/A
app pub date -
Oct 13, 1992
filing date -
Aug 26, 1988
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Abstract
A phosphatidylinositol (PI)-linked form of the LFA-3 polypeptide, which binds to CD2 molecules on the surface of T lymphocytes, in provided. Soluble polypeptides derived from the native sequence are also disclosed. DNA sequences, vectors, and transformed unicellular hosts useful for making these polypeptides are provided. Methods for using the LFA-3 polypeptides in therapy an diagnosis are described.
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