Synthesis of acyl cyanides in an anhydrous reaction medium
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United States of America Patent
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Oct 4, 1994
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Mar 23, 1993
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May 19, 1989
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Abstract
The acyl cyanides (nitriles), notably benzoyl cyanide, are prepared by reacting an acid halide with an alkali metal cyanide, in an anhydrous solvent medium, in the presence of an alkylene oxide compound and a polar compound other than water, e.g., glycerol, ethylene glycol, formamide or a sugar derivative.
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