Thiazolidine-2,4-dione derivatives, their salts and their preparation processes
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United States of America Patent
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Aug 30, 1994
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N/A
app pub date -
Oct 22, 1992
filing date -
Feb 25, 1991
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Expired
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Abstract
The present invention provides novel thiazolidine-2,4-dione derivatives possessing blood sugar-lowering action and aldose reductase-inhibitory action, their salts, their preparative processes and drugs containing them, and relates to thiazolidine-2,4-dione derivatives represented by a general formula (1) ##STR1## [wherein R.sup.1 and R.sup.2 denote identically or differently hydrogen atoms or lower alkyl groups, R.sup.3 denotes a phenyl group, naphthyl group, benzoyl group or 5-membered or 6-membered heteroring and its benzene-condensed ring, which may have one or more substituents, A denotes a carbonyl group, sulfonyl group or bonding hand, and B denotes a lower alkylene, lower alkenylene or bonding hand], or their salts, or thiazolidine-2,4-dione derivatives represented by a general formula (2) ##STR2## [wherein R.sup.4 denotes a hydrogen atom or lower alkyl group, and R.sup.1 and R.sup.3 are same as above ], or their salts.
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