Stable radiometal antibody immunoconjugates

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United States of America Patent

PATENT NO 5334729
SERIAL NO

07787244

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Abstract

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The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials.

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Patent Owner(s)

Patent OwnerAddress
BROOKHAVEN SCIENCE ASSOCIATES40 BROOKHAVEN AVENUE BLDG 460 UPTON NY 11973-5000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gestin, Jean-Francois Oudon, FR 6 21
Mease, Ronnie C Coram, NY 50 529
Srivastava, Suresh C Setauket, NY 64 623

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  • 12 Citation Count
  • C07D Class
  • 86.17 % this patent is cited more than
  • 31 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges42314341826720745622301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +01002003004005006007008009001000110012001300140015001600

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