Prostate-derived mitogen
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United States of America Patent
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Jul 26, 1994
Issued Date -
N/A
app pub date -
May 24, 1989
filing date -
Jan 2, 1986
priority date (Note) -
Expired
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Abstract
A prostate-derived growth factor is disclosed which has a mol. wt. of about 28 kDa, an NH.sub.2 -terminal sequence substantially identical to the NH.sub.2 -terminal sequence of the 6 kDa mature rat EGF, potent mitogenic activity against NRK cells without additional carboxy terminal processing to the mature 6 kDa EGF molecular species, cross-reacts with antisera against rat EGF and its mitogenic activity is blocked by anti-EGF receptor antisera.
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