Melanin formation-inhibitory protein, and its preparation and uses

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United States of America Patent

PATENT NO 5331091
SERIAL NO

08109249

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Abstract

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A novel melanin formation-inhibitory protein, which has a molecular weight of 90,000.+-.20,000 and a pI of 5.5.+-.0.5, exerts a tyrosinase formation-inhibitory activity in pigment cells but does not substantially inhibit the inherent tyrosinase activity. Thus, the protein is advantageously used as a pharmaceutical and as a cosmetic in the prevention and/or treatment for local chromatosises such as chloasma, ephelis and sunburn, as well as for systemic chromatosises such as addisonism.

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Patent Owner(s)

Patent OwnerAddress
KABUSHIKI ET AL5-4 SHINBASHI 6-CHOME DIK-MANSHON-SHINBASHI 219 MINATO-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukuda, Shigeharu Okayama, JP 90 478
Kurimoto, Masashi Okayama, JP 87 461
Suemoto, Yasuo Okayama, JP 2 4

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