Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone

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United States of America Patent

PATENT NO 5329008
SERIAL NO

08044339

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Abstract

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Synthesis of the triol of the following formula (I) from an alcohol of the formula (IV): ##STR1## via steps including protecting and then cyanating the alcohol to yield a cyanide, isomerization of the double bond, hydrolysis followed by reduction of the cyanide back to an alcohol and cis-dihydroxylation of the double bond.

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Patent Owner(s)

Patent OwnerAddress
GLAXO INCLEGAL-PATENT GROUP 5 MOORE DRIVE RTP NC 27709

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bray, Brian L Graham, NC 9 28
Partridge, John J Chapel Hill, NC 51 493

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