Stable free radical containing contrast media
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United States of America Patent
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Jun 21, 1994
Grant Date -
N/A
app pub date -
Oct 29, 1990
filing date -
Jul 19, 1988
priority date (Note) -
Expired
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Abstract
The present invention relates to a method of generating a magnetic resonance image of a sample comprising introducing into the sample a physiologically tolerable deuterated stable free radical, exposing the sample to first and second radiations of frequencies selected respectively to excite nuclear spin transitions in selected nuclei in the sample and to excite electron spin resonance transitions of the free radical coupled to nuclear spin transitions of at least some of the nuclei, detecting free induction decay signals from the sample, and generating a magnetic resonance image from these signals.
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