Enzymatic resolution of a racemic mixture of gamma-amino acids using penicillin acylase
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United States of America Patent
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May 31, 1994
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app pub date -
Jul 17, 1992
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Jul 17, 1992
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Abstract
The present invention relates to the enzymatic resolution of a racemic mixture of stereospecific, pharmaceutically useful in vivo inhibitors of .gamma.-aminobutyric acid transaminase (GABA-T), specifically .gamma.-ethynyl GABA, .gamma.-vinyl GABA and .gamma.-allenyl GABA using penicillin acylase (PA).
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