Substituted guanidines having high binding to the sigma receptor and the use thereof
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United States of America Patent
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May 17, 1994
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N/A
app pub date -
Feb 25, 1993
filing date -
Jul 10, 1986
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Abstract
N,N-disubstituted-guanidines, e.g., of the formula ##STR1## wherein R and R' are substituted or unsubstituted hydrocarbon groups. Methods are provided for the treatment of psychosis and hypertension by administering an effective amount of an N,N'-disubstituted guanidine which, preferably, has a high affinity for the sigma receptor.
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