Method for the detection of mucopolysaccharide storage diseases
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United States of America Patent
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May 10, 1994
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app pub date -
Dec 9, 1991
filing date -
May 13, 1988
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Abstract
A method for screening a patient for mucopolysaccharidoses is provided in which sample urine absorbed onto a porous sheet and dried is extracted with water. 1,9-dimethylmethylene blue dye reagent in buffer is added to the aqueous extract to produce a test solution which is assessed spectrophotometrically for color change indicative of mucopolysaccharidoses. The invention is particularly applicable to rapid and reliable mass screening and diagnosis of newborn infants.
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