Compositions containing a 4-quinolone derivative complexed with a divalent metal ion
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United States of America Patent
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Apr 19, 1994
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N/A
app pub date -
Aug 9, 1991
filing date -
Aug 10, 1990
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Abstract
The present invention concerns a fluid pharmaceutical composition intended to be brought into contact with a physiological fluid, characterized in that it contains, as active principle, at least one 4-quinolone derivative complexed with a divalent metal ion selected from Cu.sup.++, Zn.sup.++ and Mg.sup.++, the said complex being in the form of particles of a size compatible with parenteral or ophthalmic administration, in suspension in a fluid dispersant and not being subject to a crystalline growth phenomenon during storage of the said composition; the invention also provides a process for preparing a pharmaceutical composition of this type.
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