Chemotactic test apparatus and method
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United States of America Patent
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Apr 12, 1994
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app pub date -
Aug 20, 1992
filing date -
Aug 20, 1992
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Abstract
The present invention is a single site or multiple site chemotaxis test apparatus or chemotaxis chamber for measuring the effect of concentration gradients of diffusible chemicals upon the directional response of biological cells. The chemotactic test apparatus of the present invention comprise two compartments separated by a thin passage. The dimensions of the thin passage are selected such that cells cannot flow through the thin passage, but must deform themselves by flattening out and then 'crawl' or migrate through the passage. These chambers can be used to study the migration or orientation of mobile adherent or non-adherent cells.
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