Cell lines produced by transforming leukocytes of fish with oncogenes and physiologically active substances produced by the cell lines
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United States of America Patent
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Mar 29, 1994
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N/A
app pub date -
Mar 3, 1992
filing date -
Mar 4, 1991
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Expired
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Abstract
The present invention provides cell lines capable of indefinite growth which are produced by transforming leukocytes isolated from peripheral blood of fish with a oncogene, a method of establishing the cell line, a method of recovering immunologically active substances from the culture of the cell lines. It has been difficult to maintain continuous cultures of fish leukocytes. The present invention provides cell lines capable of indefinite growth and a method of producing immunologically active substances, e.g., immunologically acitive substances, using these cell lines.
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