Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases

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United States of America Patent

PATENT NO 5286726
SERIAL NO

07508873

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Abstract

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This invention relates to certain conjugates of folates and antifolates with difluoroglutamic acid which are useful in the treatment of patients suffering from certain neoplastic diseases including leukemia, melanomas, carcinomas, sarcomas and mixed neoplasias.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MICHIGAN THE1230 EISENHOWER PLACE ANN ARBOR MI 48108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bey, Philippe Cincinnati, OH 49 822
Coward, James K Ann Arbor, MI 4 48
McGuire, John J Kenmore, NY 3 44

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