Method and composition for ameliorating tissue damage due to ischemia and reperfusion
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United States of America Patent
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Feb 15, 1994
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N/A
app pub date -
Dec 31, 1991
filing date -
Dec 31, 1991
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Abstract
A method of inhibiting tissue damage in warm blooded animals related to reperfusion of tissues after extended periods of ischemia is presented. The method comprises treatment prior to a planned ischemic event or up to six hours after an unplanned ischemic event with an effective amount of monophosphoryl lipid A or 3-deacylated monophosphoryl lipid A. Pharmaceutical compositions for the treatment are also disclosed.
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