Biologically active drug polymer derivatives and method for preparing same

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United States of America Patent

PATENT NO 5286637
SERIAL NO

08001434

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Abstract

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New biologically active drug polymer derivatives, namely peptides or protein derivatives, are useful medicaments and are represented by the generic formula: RO--(CH.sub.2 --CH.sub.2 O).sub.n --(CO)--NH--X--(CO)--NH--Z (I) wherein R represents a lower alkyl group, n is an integer comprised between 25 and 250, X when combined with adjacent NH and CO groups represents an amino acid or a dipeptide or tripeptide residue, and Z when combined with the adjacent NH group represents a biologically active peptide or protein or NH or NH.sub.2 containing drug residue.

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Patent Owner(s)

Patent OwnerAddress
DEBIO RECHERCHE PHARMACEUTIQUE SAMARTIGNY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deghenghi, Romano S.-Cergue, CH 32 724
Orsolini, Piero Martigny, CH 18 834
Sartore, Luciana Padua, IT 9 411
Veronese, Francesco Padua, IT 3 163

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