Composite living skin equivalents

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United States of America Patent

PATENT NO 5282859
SERIAL NO

07777419

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Abstract

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A composite living skin equivalent is described comprising an epidermal layer of cultured keratinocyte cells, a layer of non-porous collagen, and a dermal layer of cultured fibroblast cells in a porous cross-linked collagen sponge matrix. Preferably the non-porous collagen is Type 1, Type 3 or mixtures of Types 1 and 3 bovine collagen, which has been pepsin treated. A process for preparing the skin equivalent is described, as well as a test kit for in vitro testing of the skin equivalent. The skin equivalent has use for skin grafting as well as in vitro testing of the effects of various substances on skin.

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Patent Owner(s)

Patent OwnerAddress
ORTEC INTERNATIONAL INCAUDUBON BUSINESS & TECHNOLOGY CENTER 3960 BROADWAY @ 166TH STREET NEW YORK NY 10032

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eisenberg, Mark 6 Lord Howe Street, Dover Heights, NSW 2030, AU 5 162

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