Immunoassay device for continuous monitoring
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United States of America Patent
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Jan 25, 1994
Issued Date -
N/A
app pub date -
Mar 27, 1991
filing date -
Oct 2, 1989
priority date (Note) -
Expired
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Abstract
A device and process for detecting the presence of organic molecular analytes in a fluid comprising a first binding component having a predetermined first affinity for specifically reversibly binding an analyte, a molecular conjugate of the analyte with a signal generating molecule that generates a detectable signal, and a second binding component having a predetermined second affinity for reversibly binding the signal generating molecule. In the presence of analyte, a fluid conducting system allows competitive binding of the analyte with the molecular conjugate and causes displacement of the conjugate and conducts the displaced conjugate to the second binding component. The signal generating molecule generates a detectable signal distinguishing binding thereof at the first or second binding components thereby indicating the presence of the analyte in the fluid.
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