Method for continuously determining concentration of chloride ions and bromide ions contained in serum
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United States of America Patent
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Dec 28, 1993
Grant Date -
N/A
app pub date -
Jul 17, 1992
filing date -
Jul 19, 1991
priority date (Note) -
Expired
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Abstract
A method is disclosed for determining the concentration of chloride ions and bromide ions employing one and the same serum specimen and one measuring electrode assembly consisting of a working electrode, a counter electrode and a reference electrode which is covered with a polymer film having fine porosity being disposed in a serum specimen. The potential level of the working electrode is cyclically changed within the first predetermined range to determine the total amount of coulombs based on the total amount of chloride ions and bromide ions present with specimen. Then the potential level of the working electrode is cyclically changed within the second predetermined range to determine the amount of coulombs attributable to bromide ions and subsequently the amount of coulombs attributed to the chloride ions concentration is calculated by subtracting the latter from the former and finally determining both ion concentrations by referring to a calibration curve.
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