Method and apparatus for localization of intracerebral sources of electrical activity
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United States of America Patent
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Nov 23, 1993
Grant Date -
N/A
app pub date -
Oct 5, 1992
filing date -
Oct 5, 1992
priority date (Note) -
Expired
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Abstract
Signals from plural electrodes placed at known positions on the head of an individual are digitized and processed in a computer processor which includes a bank of spatial filters. The filters are designed to meet a linearly constrained minimum variance criterion so that they each substantially pass signal energy from a location within the brain known with respect to the electrodes while rejecting signal energy from other locations within the brain. The outputs of the filters can be used to estimate the signal power at each of the locations in the brain, or the dipole moment at each location, and this information can be displayed on a display device to provide a map of source activity within the brain. The spatial filters do not require prior knowledge of the number of sources, and the number of discrete sources can be identified as well as the location, power, and dipole moment of the sources. This information can be used when a stimulus is applied to the individual to determine the regions of the brain which respond to the stimulus, or to localize neural activity in the brain to identify the location of pathology within the brain.
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