Tablets and granulates containing mesna as active substance

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United States of America Patent

PATENT NO 5262169
SERIAL NO

07730178

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain: 0.01-1 parts by weight of a binding agent 0.03-0.4 parts by weight of a disintegrant 0.01-0.2 parts by weight of a lubricant and 0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.

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Patent Owner(s)

  • ASTA MEDICA AKTIENGESELLSCHAFT;DEGUSSA AG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Engel, Jurgen Alzenau, DE 116 1036
Milsmann, Eckhard Bielefeld, DE 6 98
Sauerbier, Dieter Werter, DE 19 198

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