Site-specific modification of the candida tropicals genome

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United States of America Patent

PATENT NO 5254466
SERIAL NO

07432091

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Abstract

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The POX genes of C. tropicalis are disrupted resulting in the complete blockage of the beta-oxidation pathway in the strain. Fermentation of C. tropicalis cells having disrupted genes on alkane, fatty acid and fatty acid ester substrates produces substantially pure dicarboxylic acids in substantially quantitative yield.

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COGNIS CORPORATION2500 RENAISSANCE BOULVARD SUITE 200 GULPH MILLS PA 19406

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deanda, Kristine Graton, CA 1 41
Eirich, L Dudley Santa Rosa, CA 19 196
Picataggio, Stephen Santa Rosa, CA 31 370

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  • 41 Citation Count
  • C12P Class
  • 97.06 % this patent is cited more than
  • 32 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1075103111101 - 1011 - 2021 - 3031 - 4041 - 5051 - 60100 +05101520253035404550556065707580

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