Methods for inhibiting neoplastic cell proliferation using platelet factor 4
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United States of America Patent
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Sep 28, 1993
Issued Date -
N/A
app pub date -
Apr 29, 1992
filing date -
Mar 23, 1984
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Expired
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Abstract
Novel polypeptide compositions are provided which inhibit human tumor cell growth, which may or may not stimulate autophosphorylation of pp6src and induce the release of a 52 kD polypeptide from neoplastic cells. Individual polypeptides may be isolated from mammalian blood platelets by selected extraction and purification procedures, may be synthesized or produced by hybrid DNA technology.
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