Ligands and methods for augmenting B-cell proliferation
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United States of America Patent
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Sep 21, 1993
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app pub date -
Jun 2, 1992
filing date -
Jun 13, 1986
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Abstract
A new B-cell receptor, Bp50, a 50 kilodalton polypeptide, that functions in B-cell proliferation is described. Ligands such as lymphokines, antibody molecules or the Fv fragments of antibody molecules that bind to Bp50 and augment the proliferation of activated B-cells can be used to regulate B-cell proliferation or differentiation.
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