Pt(IV) complexes as anti-tumor agents
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United States of America Patent
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Sep 14, 1993
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app pub date -
Jul 1, 1991
filing date -
Feb 2, 1988
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Abstract
A Pt(IV) complex of the formula ##STR1## wherein A and A' are NH.sub.3 or an amino group; R and R.sup.1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.
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