Carbocyclic adenosine analogs useful as immunosuppressants

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United States of America Patent

PATENT NO 5244896
SERIAL NO

07824411

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to novel carbocyclic adenosine compounds of the formula (1) ##STR1## wherein the hydroxy substituent on the cyclopentanyl ring is in the CIS configuration relative to the bicyclic substituent, Y.sub.3, Y.sub.7, Y.sub.8 and Y.sub.9 are each independently nitrogen or a CH group, Q is NH.sub.2, halogen or hydrogen, and Z is hydrogen, halogen, or NH.sub.2 ; or a pharmaceutically-acceptable salt thereof, and to their use as immunosuppressants.

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Patent Owner(s)

Patent OwnerAddress
AVENTIS HOLDINGS INC3711 KENNETT PIKE GREENVILLE DE 19807

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borcherding, David R Overland Park, KS 25 182
Cole, Douglas L Carlsbad, CA 192 1362
Edwards, III Carl K Olathe, KS 23 134
Esser, Ronald E Kansas City, MO 14 59

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