In vitro method of inhibition of HIV using transforming growth factor-.beta.
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United States of America Patent
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Aug 17, 1993
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N/A
app pub date -
Aug 25, 1988
filing date -
Aug 25, 1988
priority date (Note) -
Expired
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Abstract
The use of TGF-.beta. to inhibit HIV infection and/or replication is described. Both mature and precursor forms of TGF-.beta. are efficacious in inhibiting production of HIV. The TGF-.beta. used to inhibit HIV may be obtained from natural sources or may be produced by recombinant DNA or chemical synthetic techniques. TGF-.beta.1 and/or TGF-.beta.2 may be used. Additionally, hybrid TGF-.beta.1/.beta.2 molecules may also be utilized.
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