Recombinant antibodies and methods for their production in which surface residues are altered to cysteine residues for attachment of effector or receptor molecules

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United States of America Patent

PATENT NO 5219996
SERIAL NO

07353634

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an altered antibody molecule wherein a residue in a surface pocket on the molecule has been changed to a cysteine residue to introduce a thiol group in the surface pocket and a process for its production by recombinant DNA technology.

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Patent Owner(s)

  • CELLTECH LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adair, John R High Wycombe, GB 3 194
Bodmer, Mark W Oxfordshire, GB 1 146
Lyons, Alan H Maidenhead, GB 1 146
Owens, Raymond J Henley-on-Thames, GB 1 146
Whittle, Nigel R Surrey, GB 1 146

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