Method of separating a peptide from a resin

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United States of America Patent

PATENT NO 5200507
SERIAL NO

07684286

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Abstract

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In solid phase peptide synthesis, resin-bound peptide is treated with hydrogen fluoride so as to cleave the peptide from the resin and form a first mixture of peptide, hydrogen fluoride and resin. The resin is removed from the first mixture so as to provide a resin-free second mixture including the polypeptide and the hydrogen fluoride. The polypeptide of the second mixture then is separated from the hydrogen fluoride.

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Patent Owner(s)

Patent OwnerAddress
MALLINCKRODT SPECIALTY CHEMICALS COMPANY16305 SWINGLEY RIDGE RD A CORP OF DE CHESTERFIELD MO 63017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chieng, Paul C St. Louis, MO 6 56

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