Method of preventing chlorohydrocarbon toxicity using sterol derivatives
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United States of America Patent
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Mar 30, 1993
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app pub date -
Apr 1, 1991
filing date -
Jan 29, 1988
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Abstract
Ionizable congeners of aromatic and aliphatic alcohols provide potent cytoprotective properties in vivo and in vitro. Alpha-tocopherol succinate, cholesteryl succinate, cholesteryl sulfate, dihydrocholesterol succinate, dihydrocholesterol sulfate, and ergosterol analogs are particularly good cytoprotective agents. In addition, the tris salts of these compounds have superior cytoprotective properties.
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