Sterile aerobic fermentation process
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United States of America Patent
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Mar 30, 1993
Issued Date -
N/A
app pub date -
May 11, 1989
filing date -
May 11, 1988
priority date (Note) -
Expired
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Abstract
The present invention is directed to a fermentation process and a fermenter, wherein aeration is improved by injecting substantially pure oxygen into culture medium by outside the fermenter means including a venturi located outside the main body of the fermenter. The oxygen is preferably injected at the throat of the venturi. The volume of the culture medium outside the fermenter is not greater than 5% of the total volume of the culture medium. The invention is particularly suitable for use in the fermentation of viscous cultures, such as cultures of filamentous fungi.
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