Modified antibodies
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United States of America Patent
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Mar 16, 1993
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N/A
app pub date -
Sep 7, 1990
filing date -
Sep 7, 1990
priority date (Note) -
Expired
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Abstract
Modified antibodies are disclosed which have been modified by chemical conjugation with a heterobifunctional reagent, such as SPDP. The use of these modified antibodies in the diagnosis and therapy of cancer and other mammalian disease is also disclosed. Diagnostic uses include immunoscintography. The modified antibodies may be further conjugated with labels or biologically active molecules for use in such diagnosis and therapy. The modified antibodies may also be formulated into pharmaceutical compositions for these purposes.
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