Process for producing non-ionic radiographic contrast media utilizing N-allylation
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United States of America Patent
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Mar 2, 1993
Issued Date -
N/A
app pub date -
Jul 5, 1990
filing date -
Oct 20, 1983
priority date (Note) -
Expired
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Abstract
Methods are provided for substituting aromatic carboxylic acids and derivatives thereof and amino substituted aromatic carboxylic acids and derivatives thereof, by forming imides and imide-amides, respectively, by acylation with aliphatic carboxylic acids, substituting at least one nitrogen atom under mild basic conditions with an aliphatic compound having as alkylating agent a displaceable functionality and removing undesired acyl groups, as appropriate.
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