Hantaan virus strain ROK84/105 and vaccine therefor
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United States of America Patent
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Feb 2, 1993
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N/A
app pub date -
Nov 16, 1989
filing date -
Nov 18, 1988
priority date (Note) -
Expired
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Abstract
The present invention relates to Hantaan virus and a vaccine therefor. The Hantaan virus vaccine can be prepared as follows: The Hantaan virus ROK84/105 strain isolated from the human body as a seed strain, injected to one-day-old suckling mouse or rat, which is raised for about 10 days. Thereafter, the head of the mouse or rat is cut apart after paralyzing the mouse or rat to take the brain, the brain is treated with ethyl alcohol and protamine sulfate solution, the resultant is purified and inactivated, and an adjuvant is added to the final product.
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