Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base, with elimination, in solution, of the bitter taste, burning of the throat and intestinal toxicity
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United States of America Patent
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Jan 19, 1993
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N/A
app pub date -
Jun 13, 1989
filing date -
Jul 12, 1988
priority date (Note) -
Expired
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Abstract
Anti-inflammatory pharmaceutical compositions with an ibuprofen base which eliminate the bitter taste, the burning in the throat and the topical toxicity at the level of the intestinal wall when their effervescent aqueous solutions are taken. The proportions among the main ingredients of each dose are the following: ibuprofen, 200 to 800 mg or ibuprofen sodium salt, 221.3 to 885.2 mg; sodium bicarbonate, 2.100 to 8.402 g; and citric acid, 0.450 to 1.800 g.
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