Liposomal-polyene preliposomal powder and method for its preparation

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United States of America Patent

PATENT NO 5178875
SERIAL NO

07640707

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Abstract

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A method is disclosed for preparing a stable preliposomal powder which, when reconstituted with water or saline solution, forms a suspension of liposomes containing a polyene drug, such as nystatin. The method involves the steps of combining at least one phospholipid with a first organic solvent to form a first solution, adding a clarifying amount of water to the first solution, combining a polyene with a second organic solvent to form a second solution, combining the first and second solutions to produce a substantially clear combined solution, and then removing the organic solvents, leaving a powder.

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Patent Owner(s)

Patent OwnerAddress
ARGUS PHARMACEUTICALS INC A DE CORP3400 RESEARCH FOREST DRIVE THE WOODLANDS TX 77381

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lenk, Robert P New Waverly, TX 28 1224
Lopez-Berestein, Gabriel Houston, TX 54 1103
Mehta, Reeta Houston, TX 9 172

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