Phthalocyanine photosensitizers for photodynamic therapy
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United States of America Patent
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Nov 24, 1992
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app pub date -
Jul 17, 1990
filing date -
Jul 17, 1990
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Abstract
The present invention relates to a series of novel phthalocyanine compositions (or compounds) suitable for use as photosensitizers for photodynamic therapy. Specifically, the invention relates to a series of new aluminum (Al) and/or silicon (Si) phthalocyanines having substituted amine or quaternary ammonium axial ligands attached to the central metal, and the use of these new phthalocyanine compositions for the treatment of cancer through photosensitization. Moreover, the present invention is directed to the methods of preparing these compositions for use in photodynamic therapy.
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