Heterocyclic ketones
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United States of America Patent
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Nov 17, 1992
Grant Date -
N/A
app pub date -
May 11, 1988
filing date -
May 11, 1987
priority date (Note) -
Expired
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Abstract
The invention provides a series of novel heterocyclic ketones of formula I ##STR1## and pharmaceutically acceptable base-addition salts thereof, in which the values of R.sup.4, L, A, X and Q have the meanings defined in the following specification. The compounds of formula I are inhibitors of human leukocytic elastase. The invention also provides pharmaceutical compositions containing a compound of formula I, or a pharmaceutically acceptable base-addition salt thereof, and processes and intermediates for the manufacture of compounds of formula I.
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