Preparation of labelled triglyceride oils by cultivation of microorganisms
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United States of America Patent
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Nov 17, 1992
Grant Date -
N/A
app pub date -
May 21, 1990
filing date -
May 21, 1990
priority date (Note) -
Expired
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Abstract
Labelled triglyceride oils are produced for use in diagnostic breath tests. The process involves the cultivation of microorganisms capable of producing the oils in an appropriately controlled environment wherein the microorganisms are fed .sup.12 C or .sup.14 C labeled carbon substrates to induce the microorganisms to produce the labeled oils. The preferred labelled carbon substrate is a substrate containing .sup.12 C. The oil produced is preferrably enriched in oleic acid. The microorganisms can be induced to produce the oil by nitrogen depletion during cultivation.
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