Heterocyclic compounds and their preparation and pharmaceutical formulation

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United States of America Patent

PATENT NO 5162345
SERIAL NO

07673510

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Abstract

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Compounds are described of the formula: ##STR1## and physiologically acceptable salts thereof, in which R.sub.1 -R.sub.7 are defined hereinafter. The compounds represented by formula (I) reduce intracellular calcium ion concentration by limiting transmembranal calcium ion concentration and thus may be useful for the treatment of cardiovascular disorders such as hypertension.

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Patent Owner(s)

Patent OwnerAddress
GLAXO S P AI-37100 VERONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borthwick, Alan D London, GB2 12 29
Gaviraghi, Giovanni Verona, IT 24 155
Micheli, Dino Modena, IT 9 27
Pieraccioli, Daniele Verona, IT 9 27
Semeraro, Claudio Bresso, IT 19 54

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