Solid oral dosage forms of ifosfamide
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United States of America Patent
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Oct 27, 1992
Grant Date -
N/A
app pub date -
Jul 24, 1991
filing date -
Aug 3, 1990
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Abstract
Solid oral ifosfamide formulations comprising a capsule containing a mass which consists essentially of the active substance ifosfamide and microcrystalline cellulose, or in the form of tablets which contain, in relation to one part by weight of ifosfamide, 0.1-1.0 parts by weight of tribasic calcium phosphate and 0.04-0.4 parts by weight of polyethylene glycol as well as in addition, related to the weight of the tablet 5-60% by weight of a filling and flow regulating agent 1-10% by weight of a disintegrant 0.1-10% by weight of an antiadhesion agent and 0.1-80% by weight of a binding agent.
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