Method of inhibiting progenitor cell proliferation
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United States of America Patent
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Sep 22, 1992
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N/A
app pub date -
Nov 13, 1989
filing date -
Nov 13, 1989
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Expired
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Abstract
The invention comprises a factor having the following characteristics: a) It inhibits granulocyte-macrophage colony and cluster formation; b) It has a molecular weight of about 8 kDa as determined by SDS-PAGE; c) It has a weak anionic charge at pH 7.4 as shown by anion exchange chromatography; d) It has a flattened isoelectric titration curve as shown by anion exchange chromatography; and e) It is a protein. The invention also comprises methods of making and using the factor and compositions comprising the factor.
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