Surface modified drug nanoparticles
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United States of America Patent
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Sep 8, 1992
Grant Date -
N/A
app pub date -
Jan 25, 1991
filing date -
Jan 25, 1991
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals.
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