Chlorination of sugars
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United States of America Patent
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Aug 4, 1992
Grant Date -
N/A
app pub date -
Jul 9, 1990
filing date -
Jul 9, 1990
priority date (Note) -
Expired
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Abstract
A process for the chlorination of sucrose or a derivative thereof, comprises reaction of the sucrose or derivative thereof with thionyl chloride and a nitrogen base at a ratio of about 1 molar equivalent (ME) of thionyl chloride and about 1 ME of base for every ME of free hydroxyl, in a non-reactive moderately polar solvent. The process is particularly suitable for the preparation of sucralose.
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